Protein Quantification features a standardized discovery proteomics service based on Hyper Reaction Monitoring (HRM-MS™), a next-generation proteomics technology invented at Biognosys for quantification of complete proteomes, or targeted proteomics solutions for protein-of-interest quantification using MRM/PRM.
Biognosys’ Discovery Proteomics (HRM-MS™) enables hypothesis-free quantification of thousands of proteins per sample from virtually any fluid or tissue. This allows the identification of significantly regulated proteins between different conditions (e.g. treated/untreated, healthy/diseased).
The Protein Quantification service features a proven HRM workflow with a deep proteome profile and a fast turnaround time of 5-6 weeks for standard projects. It is ideal for researchers looking for a deep hypothesis-free proteome quantification service.
Post-translational modification analysis and other customized services are also available upon request.
Learn more about the revolutionary next-generation proteomics, Hyper Reaction Monitoring (HRM™) in our technology section.
Learn about Biognosys tools that enable you to transfer HRM technology to your own lab.
The unbiased Protein Quantification service can be carried out for virtually any species and biological matrix.
Detailed information for the most frequently requested sample types:
|Sample preparation protocols available||yes||yes||yes||yes||yes|
|# of proteins typically identified in the sample||3’000-10’000||3’000-10’000||300-600 (depleted
|Sample amount required||5-10 mg||105-106 cells||5-10 ul||100-200 ul||50-100 ul|
Targeted Protein Quantification is a customized targeted proteomics service based on Multiple or Parallel Reaction Monitoring (MRM and PRM). MRM and PRM are targeted proteomics techniques that offer highly specific and sensitive quantification of your proteins of interest in complex biological samples.
The targeted proteomics service includes sample preparation and assay development with stable isotope peptides for absolute or relative quantification of the selected proteins. The LC-MS measurements of your samples can be performed in our state-of-the-art proteomics lab or the method can be transferred to your facility. Targeted proteomics allows a high-throughput quantification of up to 100 proteins and is ideal for researchers interested in absolute quantification of the selected proteins in hundreds or thousands of samples.
Biognosys is committed to providing the best possible results to our customers. We consider confidentiality, proactive communication, and structured project management as key factors in a successful customer relationship. Service projects are usually structured in the following way:
1. Project Set-up
2. Project Execution
3. Project Reporting
The results are presented and discussed with you in a seminar or webinar and delivered electronically in PDF and Excel formats that contain:
*relevant for discovery proteomics projects
Let us help you do great proteomics!
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